Cargando…

Lymphocytes of Type 2 Diabetic Women Carry a High Load of Stable Chromosomal Aberrations : A Novel Risk Factor for Disease-Related Early Death

OBJECTIVE—Diabetes is associated with an increased risk of death in women. Oxidative stress due to chronic hyperglycemia leads to the generation of reactive oxygen species and loss of chromosomal integrity. To clarify whether diabetes is a premature aging syndrome, we determined telomere erosion dyn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boehm, Bernhard O., Möller, Peter, Högel, Josef, Winkelmann, Bernhard R., Renner, Wilfried, Rosinger, Silke, Seelhorst, Ursula, Wellnitz, Britta, März, Winfried, Melzner, Julia, Brüderlein, Silke
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570391/ https://www.ncbi.nlm.nih.gov/pubmed/18650367 http://dx.doi.org/10.2337/db08-0274

Ejemplares similares

Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study)
por: Lüblinghoff, Nicola, et al.
Publicado: (2009)

Glycated Hemoglobin Predicts All-Cause, Cardiovascular, and Cancer Mortality in People Without a History of Diabetes Undergoing Coronary Angiography
por: Silbernagel, Guenther, et al.
Publicado: (2011)

Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography—The LURIC study
por: Scharnagl, Hubert, et al.
Publicado: (2014)

Additional Use of Glycated Hemoglobin for Diagnosis of Type 2 Diabetes in People Undergoing Coronary Angiography Reveals a Subgroup at Increased Cardiovascular Risk
por: Silbernagel, Guenther, et al.
Publicado: (2011)

Genetic Analysis of Adult-Onset Autoimmune Diabetes
por: Howson, Joanna M.M., et al.
Publicado: (2011)

C-Peptide Levels Are Associated With Mortality and Cardiovascular Mortality in Patients Undergoing Angiography: The LURIC study
por: Marx, Nikolaus, et al.
Publicado: (2013)

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL)
por: Ritz, Olga, et al.
Publicado: (2013)

3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"
por: Knecht, Hans, et al.
Publicado: (2010)

Sex-related differences in length and erosion dynamics of human telomeres favor females
por: Möller, Peter, et al.
Publicado: (2009)

Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and cardiovascular health study)
por: Kleber, Marcus E, et al.
Publicado: (2010)

Molecular profiling of chordoma
por: SCHEIL-BERTRAM, STEFANIE, et al.
Publicado: (2014)

Low Free Testosterone Levels Are Associated With All-Cause and Cardiovascular Mortality in Postmenopausal Diabetic Women
por: Wehr, Elisabeth, et al.
Publicado: (2011)

Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells
por: Steinestel, Konrad, et al.
Publicado: (2014)

The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients
por: Yazdani-Biuki, Babak, et al.
Publicado: (2006)

Coronavirus genomes carry the signatures of their habitats
por: Wei, Yulong, et al.
Publicado: (2020)

Aberrant Single Exon Skipping is not Altered by Age in Exons of NF1, RABAC1, AATF or PCGF2 in Human Blood Cells and Fibroblasts
por: Mellert, Kevin, et al.
Publicado: (2011)

Genetic variation in Fcγ receptor IIa and risk of coronary heart disease: negative results from two large independent populations
por: Karakas, Mahir, et al.
Publicado: (2009)

Expression of Abelson Interactor 1 (Abi1) Correlates with Inflammation, KRAS Mutation and Adenomatous Change during Colonic Carcinogenesis
por: Steinestel, Konrad, et al.
Publicado: (2012)

Circulating Dopamine and C-Peptide Levels in Fasting Nondiabetic Hypertensive Patients: The Graz Endocrine Causes of Hypertension study
por: Tomaschitz, Andreas, et al.
Publicado: (2012)

Letter to the Editor: Comments on “Obesity associated with a novel mitochondrial tRNA(Cys) m.5802A>G mutation in a Chinese family”
por: Finsterer, Josef
Publicado: (2020)

Molecular Characterization of Putative Chordoma Cell Lines
por: Brüderlein, Silke, et al.
Publicado: (2010)

Changes in insulin sensitivity and insulin secretion during pregnancy and post partum in women with gestational diabetes
por: Skajaa, Gitte Oeskov, et al.
Publicado: (2020)

Single-molecule Study on the Temperature-sensitive Reaction of F(1)-ATPase with a Hybrid F(1) Carrying a Single β(E190D)
por: Enoki, Sawako, et al.
Publicado: (2009)

Dysregulation of Placental Endothelial Lipase in Obese Women With Gestational Diabetes Mellitus
por: Gauster, Martin, et al.
Publicado: (2011)

Aberrant Thyroid Function Tests in a Patient Taking Biotin Supplements
por: Latif, Zara, et al.
Publicado: (2019)

Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling
por: Vestergaard, Esben Thyssen, et al.
Publicado: (2008)

Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid
por: Landmesser, Anne, et al.
Publicado: (2021)

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance
por: Huynh, Frank K., et al.
Publicado: (2010)

An Aberrant Case of Large Submandibular Gland Sialolith With Obstructive Sialadenitis in a Young Female
por: Attar, Wajid, et al.
Publicado: (2023)

Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes
por: Støy, Julie, et al.
Publicado: (2015)

Decay-accelerating factor (DAF, CD55) in normal colorectal mucosa, adenomas and carcinomas.
por: Koretz, K., et al.
Publicado: (1992)

Expression of CD59, a complement regulator protein and a second ligand of the CD2 molecule, and CD46 in normal and neoplastic colorectal epithelium.
por: Koretz, K., et al.
Publicado: (1993)

Healthy grocery delivery in the usual care for adults recovering from an acute coronary event: protocol for a three-arm randomised controlled trial
por: Reynolds, Andrew N, et al.
Publicado: (2023)

Bioactivation of food genotoxicants 5-hydroxymethylfurfural and furfuryl alcohol by sulfotransferases from human, mouse and rat: a comparative study
por: Sachse, Benjamin, et al.
Publicado: (2014)

Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
por: Morgan, Thomas M, et al.
Publicado: (2011)

Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling
por: Liszka, Aleksandra, et al.
Publicado: (2020)

BRCA2 Mutations and Triple-Negative Breast Cancer
por: Meyer, Peter, et al.
Publicado: (2012)

Aberrant Water Homeostasis Detected by Stable Isotope Analysis
por: O'Grady, Shannon P., et al.
Publicado: (2010)

Soluble pattern recognition molecules: Guardians and regulators of homeostasis at airway mucosal surfaces
por: Smole, Ursula, et al.
Publicado: (2020)

An Aberrant Case of Pheochromocytoma in a Young Adult Presenting With Secondary Hypertension: A Case Report With Review of the Literature
por: Trimukhe, Deepali, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q1sas3amgq7kpfgmnlmq3a2qn2