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Association of Single Nucleotide Polymorphisms in the IL-18 Gene with Production of IL-18 Protein by Mononuclear Cells from Healthy Donors

IL-18 has proinflammatory effects and participates in both innate and adaptive cellular and humoral immunity. A number of SNPs that influence IL-18 production are found in the gene promoter region. We investigated the association of SNPs in the IL-18 promoter at −607 and −137 with the level of IL-18...

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Detalles Bibliográficos
Autores principales:	Khripko, O. P., Sennikova, N. S., Lopatnikova, J. A., Khripko, J. I., Filipenko, M. L., Khrapov, E. A., Gelfgat, E. L., Yakushenko, E. V., Kozlov, V. A., Sennikov, S. V.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570435/ https://www.ncbi.nlm.nih.gov/pubmed/18949051 http://dx.doi.org/10.1155/2008/309721

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