Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma

Vascular disrupting agents (VDAs) are able to affect selectively tumour endothelial cell morphology resulting in vessel occlusion and widespread tumour cell necrosis. However, single-agent antitumour activity of VDAs is typically limited, as tumour regrowth occurs rapidly following drug treatment. T...

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Detalles Bibliográficos
Autores principales: Fens, M H A M, Hill, K J, Issa, J, Ashton, S E, Westwood, F R, Blakey, D C, Storm, G, Ryan, A J, Schiffelers, R M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570501/
https://www.ncbi.nlm.nih.gov/pubmed/18797467
http://dx.doi.org/10.1038/sj.bjc.6604675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570501/
https://www.ncbi.nlm.nih.gov/pubmed/18797467
http://dx.doi.org/10.1038/sj.bjc.6604675

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