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PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients

The immunosuppressant azathioprine is used to prevent graft rejection after organ transplantation. To investigate whether azathioprine-associated mutagenesis contributes to the high incidence of skin tumours in organ transplant recipients (OTRs), we analysed PTCH gene mutations in 60 basal cell carc...

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Detalles Bibliográficos
Autores principales: Harwood, C A, Attard, N R, O'Donovan, P, Chambers, P, Perrett, C M, Proby, C M, McGregor, J M, Karran, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570526/
https://www.ncbi.nlm.nih.gov/pubmed/18854826
http://dx.doi.org/10.1038/sj.bjc.6604665