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Heparin Alters Viral Serpin, Serp-1, Anti-Thrombolytic Activity to Anti-Thrombotic Activity

Serine protease inhibitors (serpins) regulate coagulation and inflammation. Heparin, a glycosaminoglycan, is an important cofactor for modulation of the inhibitory function of mammalian serpins. The secreted myxoma viral serpin, Serp-1 exerts profound anti-inflammatory activity in a wide range of an...

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Detalles Bibliográficos
Autores principales:	Li, Xing, Schneider, Heather, Peters, Andrew, Macaulay, Colin, King, Elaine, Sun, Yunming, Liu, Liying, Dai, Erbin, Davids, Jennifer A., McFadden, Grant, Lucas, Alexandra
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570549/ https://www.ncbi.nlm.nih.gov/pubmed/18949070 http://dx.doi.org/10.2174/1874091X00802010006

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