Subunit Mobility and the Chaperone Activity of Recombinant αB-Crystallin

The comparison of the chaperone-like activity of native and covalently cross-linked human αB-crystallins has confirmed the important role of the subunit mobility in the chaperoning mechanism. Our data clearly demonstrate that the chaperone-like activity of α-crystallin is not only a surface phenomen...

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Detalles Bibliográficos
Autores principales: Krushelnitsky, A, Mukhametshina, N, Gogolev, Y, Tarasova, N, Faizullin, D, Zinkevich, T, Gnezdilov, O, Fedotov, V
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570560/
https://www.ncbi.nlm.nih.gov/pubmed/18949083
http://dx.doi.org/10.2174/1874091X00802010116
Descripción
Sumario:The comparison of the chaperone-like activity of native and covalently cross-linked human αB-crystallins has confirmed the important role of the subunit mobility in the chaperoning mechanism. Our data clearly demonstrate that the chaperone-like activity of α-crystallin is not only a surface phenomenon as was suggested by some researchers.

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