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Adaptive Copy Number Evolution in Malaria Parasites

Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood. The first gene in the Plasmodium folate biosynthesis pathway, GTP-cyclohydrolase I (gch1), shows extensive CNP. We provide compelling evide...

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Detalles Bibliográficos
Autores principales:	Nair, Shalini, Miller, Becky, Barends, Marion, Jaidee, Anchalee, Patel, Jigar, Mayxay, Mayfong, Newton, Paul, Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570623/ https://www.ncbi.nlm.nih.gov/pubmed/18974876 http://dx.doi.org/10.1371/journal.pgen.1000243

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