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Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City
We reviewed medical records of patients without known HIV and with positive cultures for nontuberculous mycobacteria (NTM) isolated during 2000–2003 from 1 large hospital in New York, New York. Overall, 505 patients had positive NTM cultures; 119 (24%) met the criteria for NTM disease. The differenc...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Centers for Disease Control and Prevention
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570812/ https://www.ncbi.nlm.nih.gov/pubmed/18325252 http://dx.doi.org/10.3201/eid1403.061143 |
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author | Bodle, Ethan E. Cunningham, Jennifer A. Della-Latta, Phyllis Schluger, Neil W. Saiman, Lisa |
author_facet | Bodle, Ethan E. Cunningham, Jennifer A. Della-Latta, Phyllis Schluger, Neil W. Saiman, Lisa |
author_sort | Bodle, Ethan E. |
collection | PubMed |
description | We reviewed medical records of patients without known HIV and with positive cultures for nontuberculous mycobacteria (NTM) isolated during 2000–2003 from 1 large hospital in New York, New York. Overall, 505 patients had positive NTM cultures; 119 (24%) met the criteria for NTM disease. The difference between demographic characteristics of case-patients in our study (66% female, 61% white, and 59% >60 years of age) and those of the base population as determined by regional census data was statistically significant. Estimated incidences for positive cultures, all disease, and respiratory tract disease were 17.7, 2.7, and 2.0 per 100,000 persons, respectively. More patients with rapidly growing mycobacteria (61%), Mycobacterium kansasii (70%), or M. marinum (100%) met criteria for disease than did patients with M. avium complex (MAC) (27%, (p<0.01). NTM disease in patients without HIV is increasing. Laboratory-based surveillance may be useful for detecting non-MAC and non–respiratory tract disease. |
format | Text |
id | pubmed-2570812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-25708122009-01-13 Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City Bodle, Ethan E. Cunningham, Jennifer A. Della-Latta, Phyllis Schluger, Neil W. Saiman, Lisa Emerg Infect Dis Research We reviewed medical records of patients without known HIV and with positive cultures for nontuberculous mycobacteria (NTM) isolated during 2000–2003 from 1 large hospital in New York, New York. Overall, 505 patients had positive NTM cultures; 119 (24%) met the criteria for NTM disease. The difference between demographic characteristics of case-patients in our study (66% female, 61% white, and 59% >60 years of age) and those of the base population as determined by regional census data was statistically significant. Estimated incidences for positive cultures, all disease, and respiratory tract disease were 17.7, 2.7, and 2.0 per 100,000 persons, respectively. More patients with rapidly growing mycobacteria (61%), Mycobacterium kansasii (70%), or M. marinum (100%) met criteria for disease than did patients with M. avium complex (MAC) (27%, (p<0.01). NTM disease in patients without HIV is increasing. Laboratory-based surveillance may be useful for detecting non-MAC and non–respiratory tract disease. Centers for Disease Control and Prevention 2008-03 /pmc/articles/PMC2570812/ /pubmed/18325252 http://dx.doi.org/10.3201/eid1403.061143 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Bodle, Ethan E. Cunningham, Jennifer A. Della-Latta, Phyllis Schluger, Neil W. Saiman, Lisa Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title | Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title_full | Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title_fullStr | Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title_full_unstemmed | Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title_short | Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection, New York City |
title_sort | epidemiology of nontuberculous mycobacteria in patients without hiv infection, new york city |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570812/ https://www.ncbi.nlm.nih.gov/pubmed/18325252 http://dx.doi.org/10.3201/eid1403.061143 |
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