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Mycobacterium ulcerans Disease, Peru

Eight adult patients (ages 18–58, 5 women) with Buruli ulcer (BU) confirmed by at least 2 diagnostic methods were seen in a 10-year period. Attempts to culture Mycobacterium ulcerans failed. Five patients came from jungle areas, and 3 from the swampy northern coast of Peru. The patients had 1–5 lesi...

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Autores principales: Guerra, Humberto, Palomino, Juan Carlos, Falconí, Eduardo, Bravo, Francisco, Donaires, Ninoska, Van Marck, Eric, Portaels, Françoise
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570831/
https://www.ncbi.nlm.nih.gov/pubmed/18325248
http://dx.doi.org/10.3201/eid1403.070904
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author Guerra, Humberto
Palomino, Juan Carlos
Falconí, Eduardo
Bravo, Francisco
Donaires, Ninoska
Van Marck, Eric
Portaels, Françoise
author_facet Guerra, Humberto
Palomino, Juan Carlos
Falconí, Eduardo
Bravo, Francisco
Donaires, Ninoska
Van Marck, Eric
Portaels, Françoise
author_sort Guerra, Humberto
collection PubMed
description Eight adult patients (ages 18–58, 5 women) with Buruli ulcer (BU) confirmed by at least 2 diagnostic methods were seen in a 10-year period. Attempts to culture Mycobacterium ulcerans failed. Five patients came from jungle areas, and 3 from the swampy northern coast of Peru. The patients had 1–5 lesions, most of which were on the lower extremities. One patient had 5 clustered gluteal lesions; another patient had 2 lesions on a finger. Three patients were lost to follow-up. All 5 remaining patients had moderate disease. Diverse treatments (antituberculous drugs, World Health Organization [WHO] recommended antimicrobial drug treatment for BU, and for 3 patients, excision surgery) were successful. Only 1 patient (patient 7) received the specific drug treatment recommended by WHO. BU is endemic in Peru, although apparently infrequent. Education of populations and training of health workers are first needed to evaluate and understand the full extent of BU in Peru.
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spelling pubmed-25708312009-01-13 Mycobacterium ulcerans Disease, Peru Guerra, Humberto Palomino, Juan Carlos Falconí, Eduardo Bravo, Francisco Donaires, Ninoska Van Marck, Eric Portaels, Françoise Emerg Infect Dis Research Eight adult patients (ages 18–58, 5 women) with Buruli ulcer (BU) confirmed by at least 2 diagnostic methods were seen in a 10-year period. Attempts to culture Mycobacterium ulcerans failed. Five patients came from jungle areas, and 3 from the swampy northern coast of Peru. The patients had 1–5 lesions, most of which were on the lower extremities. One patient had 5 clustered gluteal lesions; another patient had 2 lesions on a finger. Three patients were lost to follow-up. All 5 remaining patients had moderate disease. Diverse treatments (antituberculous drugs, World Health Organization [WHO] recommended antimicrobial drug treatment for BU, and for 3 patients, excision surgery) were successful. Only 1 patient (patient 7) received the specific drug treatment recommended by WHO. BU is endemic in Peru, although apparently infrequent. Education of populations and training of health workers are first needed to evaluate and understand the full extent of BU in Peru. Centers for Disease Control and Prevention 2008-03 /pmc/articles/PMC2570831/ /pubmed/18325248 http://dx.doi.org/10.3201/eid1403.070904 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Guerra, Humberto
Palomino, Juan Carlos
Falconí, Eduardo
Bravo, Francisco
Donaires, Ninoska
Van Marck, Eric
Portaels, Françoise
Mycobacterium ulcerans Disease, Peru
title Mycobacterium ulcerans Disease, Peru
title_full Mycobacterium ulcerans Disease, Peru
title_fullStr Mycobacterium ulcerans Disease, Peru
title_full_unstemmed Mycobacterium ulcerans Disease, Peru
title_short Mycobacterium ulcerans Disease, Peru
title_sort mycobacterium ulcerans disease, peru
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570831/
https://www.ncbi.nlm.nih.gov/pubmed/18325248
http://dx.doi.org/10.3201/eid1403.070904
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