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The Role of External and Matrix pH in Mitochondrial Reactive Oxygen Species Generation

Reactive oxygen species (ROS) generation in mitochondria as a side product of electron and proton transport through the inner membrane is important for normal cell operation as well as development of pathology. Matrix and cytosol alkalization stabilizes semiquinone radical, a potential superoxide pr...

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Detalles Bibliográficos
Autores principales:	Selivanov, Vitaly A., Zeak, Jennifer A., Roca, Josep, Cascante, Marta, Trucco, Massimo, Votyakova, Tatyana V.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Metabolism and Bioenergetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570889/ https://www.ncbi.nlm.nih.gov/pubmed/18687689 http://dx.doi.org/10.1074/jbc.M801019200

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