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SELDI-TOF-MS determination of hepcidin in clinical samples using stable isotope labelled hepcidin as an internal standard

BACKGROUND: Hepcidin is a 25-residue peptide hormone crucial to iron homeostasis. It is essential to measure the concentration of hepcidin in cells, tissues and body fluids to understand its mechanisms and roles in physiology and pathophysiology. With a mass of 2791 Da hepcidin is readily detectable...

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Detalles Bibliográficos
Autores principales: Ward, Douglas G, Roberts, Keith, Stonelake, Paul, Goon, Patrick, Zampronio, Cleidiane G, Martin, Ashley, Johnson, Philip J, Iqbal, Tariq, Tselepis, Chris
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571088/
https://www.ncbi.nlm.nih.gov/pubmed/18854031
http://dx.doi.org/10.1186/1477-5956-6-28