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Amplification of HER2 is a marker for global genomic instability

BACKGROUND: Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of ampli...

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Detalles Bibliográficos
Autores principales:	Ellsworth, Rachel E, Ellsworth, Darrell L, Patney, Heather L, Deyarmin, Brenda, Love, Brad, Hooke, Jeffrey A, Shriver, Craig D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571108/ https://www.ncbi.nlm.nih.gov/pubmed/18854030 http://dx.doi.org/10.1186/1471-2407-8-297

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