Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo

T cells primed in the gut-draining mesenteric lymph nodes (mLN) are imprinted to express α4β7-integrin and chemokine receptor CCR9, thereby enabling lymphocytes to migrate to the small intestine. In vitro activation by intestinal dendritic cells (DC) or addition of retinoic acid (RA) is sufficient t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hammerschmidt, Swantje I., Ahrendt, Manuela, Bode, Ulrike, Wahl, Benjamin, Kremmer, Elisabeth, Förster, Reinhold, Pabst, Oliver
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571923/
https://www.ncbi.nlm.nih.gov/pubmed/18852290
http://dx.doi.org/10.1084/jem.20080039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571923/
https://www.ncbi.nlm.nih.gov/pubmed/18852290
http://dx.doi.org/10.1084/jem.20080039

Ejemplares similares