Cargando…

Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo

T cells primed in the gut-draining mesenteric lymph nodes (mLN) are imprinted to express α4β7-integrin and chemokine receptor CCR9, thereby enabling lymphocytes to migrate to the small intestine. In vitro activation by intestinal dendritic cells (DC) or addition of retinoic acid (RA) is sufficient t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hammerschmidt, Swantje I., Ahrendt, Manuela, Bode, Ulrike, Wahl, Benjamin, Kremmer, Elisabeth, Förster, Reinhold, Pabst, Oliver
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571923/ https://www.ncbi.nlm.nih.gov/pubmed/18852290 http://dx.doi.org/10.1084/jem.20080039

Ejemplares similares

Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes
por: Pezoldt, Joern, et al.
Publicado: (2018)

Chemokine Receptor CCR9 Contributes to the Localization of Plasma Cells to the Small Intestine
por: Pabst, Oliver, et al.
Publicado: (2004)

Dietary lipids accumulate in macrophages and stromal cells and change the microarchitecture of mesenteric lymph nodes
por: Streich, Katharina, et al.
Publicado: (2020)

Characterization of resident and migratory dendritic cells in human lymph nodes
por: Segura, Elodie, et al.
Publicado: (2012)

Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets
por: Pezoldt, Joern, et al.
Publicado: (2022)

Antigen-pulsed CD8α(+) Dendritic Cells Generate an Immune Response after Subcutaneous Injection without Homing to the Draining Lymph Node
por: Smith, Adrian L., et al.
Publicado: (1999)

Lymph Node Stromal Cells From Different Draining Areas Distinctly Regulate the Development of Chronic Intestinal Inflammation
por: Basic, Marijana, et al.
Publicado: (2021)

IL-4–producing CD4(+) T cells in reactive lymph nodes during helminth infection are T follicular helper cells
por: King, Irah L., et al.
Publicado: (2009)

Cooperating Mechanisms of CXCR5 and CCR7 in Development and Organization of Secondary Lymphoid Organs
por: Ohl, Lars, et al.
Publicado: (2003)

CCL5-producing migratory dendritic cells guide CCR5(+) monocytes into the draining lymph nodes
por: Rawat, Kavita, et al.
Publicado: (2023)

Lymph Node Transplantation and Its Immunological Significance in Animal Models
por: Buettner, Manuela, et al.
Publicado: (2011)

Endothelial cell–specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation
por: Onder, Lucas, et al.
Publicado: (2013)

Cd11c(+)B220(+)Gr-1(+) Cells in Mouse Lymph Nodes and Spleen Display Characteristics of Plasmacytoid Dendritic Cells
por: Nakano, Hideki, et al.
Publicado: (2001)

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
por: Cohen, Jarish N., et al.
Publicado: (2010)

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
por: Fletcher, Anne L., et al.
Publicado: (2010)

CC Chemokine Receptor 7–dependent and –independent Pathways for Lymphocyte Homing: Modulation by FTY720
por: Henning, Golo, et al.
Publicado: (2001)

Plasmacytoid dendritic cells induce tolerance predominantly by cargoing antigen to lymph nodes
por: Kohli, Karan, et al.
Publicado: (2016)

Mesenteric lymph nodes at the center of immune anatomy
por: Macpherson, Andrew J., et al.
Publicado: (2006)

Mesenteric lymph node stromal cell‐derived extracellular vesicles contribute to peripheral de novo induction of Foxp3(+) regulatory T cells
por: Pasztoi, Maria, et al.
Publicado: (2017)

Lymph Node Stromal Cells: Mapmakers of T Cell Immunity
por: Harlé, Guillaume, et al.
Publicado: (2020)

Thymic T Cell Development and Progenitor Localization Depend on CCR7
por: Misslitz, Ana, et al.
Publicado: (2004)

Lymph-Derived Neutrophils Primarily Locate to the Subcapsular and Medullary Sinuses in Resting and Inflamed Lymph Nodes
por: de Castro Pinho, Jenny, et al.
Publicado: (2021)

Overlapping Roles of CXCL13, Interleukin 7 Receptor α, and CCR7 Ligands in Lymph Node Development
por: Luther, Sanjiv A., et al.
Publicado: (2003)

Mixed Epithelial Stromal Tumor of the Kidney With a Mesenteric Lymph Node: A Case Report and Literature Review
por: Dan, Chitramalya, et al.
Publicado: (2023)

Characterization of Leptin Receptor(+) Stromal Cells in Lymph Node
por: Jiang, Liwei, et al.
Publicado: (2022)

Mesenteric lymph node B lymphoblasts which home to the small intestine are precommitted to IgA synthesis
Publicado: (1977)

Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells
por: Halle, Stephan, et al.
Publicado: (2009)

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
por: Dubey, Lalit Kumar, et al.
Publicado: (2017)

Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's Patches
por: Okada, Takaharu, et al.
Publicado: (2002)

Natural Killer Cells Mediate Protection against Yersinia pseudotuberculosis in the Mesenteric Lymph Nodes
por: Rosenheinrich, Maik, et al.
Publicado: (2015)

Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment
por: Geem, Duke, et al.
Publicado: (2016)

Cavitatory mesenteric lymph node syndrome: A rare entity
por: Vibhuti,, et al.
Publicado: (2010)

A Neglected Issue in Ulcerative Colitis: Mesenteric Lymph Nodes
por: Sahin, Abdurrahman, et al.
Publicado: (2018)

The Utility of Diagnostic Laparoscopic Biopsy for Mesenteric and Retroperitoneal Lymph Nodes
por: Sando, Masanori, et al.
Publicado: (2017)

Mesenteric Lymph Node Recurrence of a Primary Colorectal Leiomyosarcoma
por: Beauchamp, Amélie, et al.
Publicado: (2020)

The roles of lymph node stromal cells in proliferation of lymphoid leukaemia cells.
por: Tsuda, H., et al.
Publicado: (1990)

Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
por: Novkovic, Mario, et al.
Publicado: (2018)

IL-17–induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
por: Fleige, Henrike, et al.
Publicado: (2014)

Anti-CD43 Inhibition of T Cell Homing
por: McEvoy, Leslie M., et al.
Publicado: (1997)

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells
por: Worbs, Tim, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_kusf62ir5i94rnlq82qpctme97