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Rescue of Volume-regulated Anion Current by Bestrophin Mutants with Altered Charge Selectivity
Mutations in human bestrophin-1 are linked to various kinds of retinal degeneration. Although it has been proposed that bestrophins are Ca(2+)-activated Cl(−) channels, definitive proof is lacking partly because mice with the bestrophin-1 gene deleted have normal Ca(2+)-activated Cl(−) currents. Her...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571971/ https://www.ncbi.nlm.nih.gov/pubmed/18955594 http://dx.doi.org/10.1085/jgp.200810065 |