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Contribution of the Myosin Binding Protein C Motif to Functional Effects in Permeabilized Rat Trabeculae

Myosin binding protein C (MyBP-C) is a thick-filament protein that limits cross-bridge cycling rates and reduces myocyte power output. To investigate mechanisms by which MyBP-C affects contraction, we assessed effects of recombinant N-terminal domains of cardiac MyBP-C (cMyBP-C) on contractile prope...

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Detalles Bibliográficos
Autores principales: Razumova, Maria V., Bezold, Kristina L., Tu, An-Yue, Regnier, Michael, Harris, Samantha P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571974/
https://www.ncbi.nlm.nih.gov/pubmed/18955596
http://dx.doi.org/10.1085/jgp.200810013