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Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1
The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a blo...
Autores principales: | Karnowski, Alexander, Cao, Chun, Matthias, Gabriele, Carotta, Sebastian, Corcoran, Lynn M., Martensson, Inga-Lill, Skok, Jane A., Matthias, Patrick |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571989/ https://www.ncbi.nlm.nih.gov/pubmed/18974788 http://dx.doi.org/10.1371/journal.pone.0003568 |
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