Broadening of Neutralization Activity to Directly Block a Dominant Antibody-Driven SARS-Coronavirus Evolution Pathway

Phylogenetic analyses have provided strong evidence that amino acid changes in spike (S) protein of animal and human SARS coronaviruses (SARS-CoVs) during and between two zoonotic transfers (2002/03 and 2003/04) are the result of positive selection. While several studies support that some amino acid...

Descripción completa

Detalles Bibliográficos
Autores principales: Sui, Jianhua, Aird, Daniel R., Tamin, Azaibi, Murakami, Akikazu, Yan, Meiying, Yammanuru, Anuradha, Jing, Huaiqi, Kan, Biao, Liu, Xin, Zhu, Quan, Yuan, Qing-an, Adams, Gregory P., Bellini, William J., Xu, Jianguo, Anderson, Larry J., Marasco, Wayne A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572002/
https://www.ncbi.nlm.nih.gov/pubmed/18989460
http://dx.doi.org/10.1371/journal.ppat.1000197

Ejemplares similares

Ejemplares similares