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A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates

The presence of oligomeric aggregates, which is often observed during the process of amyloid formation, has recently attracted much attention because it has been associated with a range of neurodegenerative conditions including Alzheimer's and Parkinson's diseases. We provide a description...

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Detalles Bibliográficos
Autores principales: Auer, Stefan, Meersman, Filip, Dobson, Christopher M., Vendruscolo, Michele
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572140/
https://www.ncbi.nlm.nih.gov/pubmed/19008938
http://dx.doi.org/10.1371/journal.pcbi.1000222