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Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression
The type I interferon (IFN) system is a first line of defense against viral infections. Viruses have developed various mechanisms to counteract this response. So far, the interferon antagonistic activity of influenza A viruses was mainly observed on the level of IFNβ gene induction via action of the...
Autores principales: | Pauli, Eva-K., Schmolke, Mirco, Wolff, Thorsten, Viemann, Dorothee, Roth, Johannes, Bode, Johannes G., Ludwig, Stephan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572141/ https://www.ncbi.nlm.nih.gov/pubmed/18989459 http://dx.doi.org/10.1371/journal.ppat.1000196 |
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