Cargando…
Androgen Receptor Functional Analyses by High Throughput Imaging: Determination of Ligand, Cell Cycle, and Mutation-Specific Effects
BACKGROUND: Understanding how androgen receptor (AR) function is modulated by exposure to steroids, growth factors or small molecules can have important mechanistic implications for AR-related disease therapies (e.g., prostate cancer, androgen insensitivity syndrome, AIS), and in the analysis of env...
Autores principales: | Szafran, Adam T., Szwarc, Maria, Marcelli, Marco, Mancini, Michael A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572143/ https://www.ncbi.nlm.nih.gov/pubmed/18978937 http://dx.doi.org/10.1371/journal.pone.0003605 |
Ejemplares similares
-
Androgen Receptor Mutations Associated with Androgen Insensitivity Syndrome: A High Content Analysis Approach Leading to Personalized Medicine
por: Szafran, Adam T., et al.
Publicado: (2009) -
Therapeutic androgen receptor ligands
por: Allan, George F., et al.
Publicado: (2003) -
Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis
por: Szafran, Adam T., et al.
Publicado: (2017) -
Computational Analysis of Residue-Specific Binding Free Energies of Androgen Receptor to Ligands
por: Shao, Guangfeng, et al.
Publicado: (2021) -
Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay
por: Shaw, Joseph, et al.
Publicado: (2018)