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Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation
BACKGROUND: The development of mass spectrometric techniques and fractionation methods now allows the investigation of very complex protein mixtures ranging from subcellular structures to tissues. Nevertheless, this work is particularly difficult due to the wide dynamic range of protein concentratio...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572582/ https://www.ncbi.nlm.nih.gov/pubmed/18851748 http://dx.doi.org/10.1186/1477-5956-6-27 |