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Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
BACKGROUND: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). Methods developed for normalization of WGG arrays have mostly focused on di...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572624/ https://www.ncbi.nlm.nih.gov/pubmed/18831757 http://dx.doi.org/10.1186/1471-2105-9-409 |