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Methylation screening of the TGFBI promoter in human lung and prostate cancer by methylation-specific PCR

BACKGROUND: Hypermethylation of the TGFBI promoter has been shown to correlate with decreased expression of this gene in human tumor cell lines. In this study, we optimized a methylation-specific polymerase chain reaction (MSP) method and investigated the methylation status of the TGFBI promoter in...

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Detalles Bibliográficos
Autores principales: Shah, Jinesh N, Shao, Genze, Hei, Tom K, Zhao, Yongliang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572632/
https://www.ncbi.nlm.nih.gov/pubmed/18834524
http://dx.doi.org/10.1186/1471-2407-8-284