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Methylation screening of the TGFBI promoter in human lung and prostate cancer by methylation-specific PCR
BACKGROUND: Hypermethylation of the TGFBI promoter has been shown to correlate with decreased expression of this gene in human tumor cell lines. In this study, we optimized a methylation-specific polymerase chain reaction (MSP) method and investigated the methylation status of the TGFBI promoter in...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572632/ https://www.ncbi.nlm.nih.gov/pubmed/18834524 http://dx.doi.org/10.1186/1471-2407-8-284 |