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Performance of mitochondrial DNA mutations detecting early stage cancer

BACKGROUND: Mutations in the mitochondrial genome (mtgenome) have been associated with cancer and many other disorders. These mutations can be point mutations or deletions, or admixtures (heteroplasmy). The detection of mtDNA mutations in body fluids using resequencing microarrays, which are more se...

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Detalles Bibliográficos
Autores principales: Jakupciak, John P, Maragh, Samantha, Markowitz, Maura E, Greenberg, Alissa K, Hoque, Mohammad O, Maitra, Anirban, Barker, Peter E, Wagner, Paul D, Rom, William N, Srivastava, Sudhir, Sidransky, David, O'Connell, Catherine D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572633/
https://www.ncbi.nlm.nih.gov/pubmed/18834532
http://dx.doi.org/10.1186/1471-2407-8-285