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Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase

Non-structural protein 3 (NS3) is a multifunctional enzyme possessing serine protease, NTPase, and RNA unwinding activities that are required for hepatitis C viral (HCV) replication. HCV non-structural protein 4A (NS4A) binds to the N-terminal NS3 protease domain to stimulate NS3 serine protease act...

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Detalles Bibliográficos
Autores principales:	Beran, Rudolf K. F., Pyle, Anna Marie
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Enzyme Catalysis and Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573085/ https://www.ncbi.nlm.nih.gov/pubmed/18723512 http://dx.doi.org/10.1074/jbc.M804065200

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