The Desensitization Gating of the MthK K(+) Channel Is Governed by Its Cytoplasmic Amino Terminus

The RCK-containing MthK channel undergoes two inactivation processes: activation-coupled desensitization and acid-induced inactivation. The acid inactivation is mediated by the C-terminal RCK domain assembly. Here, we report that the desensitization gating is governed by a desensitization domain (DD...

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Detalles Bibliográficos
Autores principales: Kuo, Mario Meng-Chiang, Maslennikov, Innokentiy, Molden, Brent, Choe, Senyon
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573919/
https://www.ncbi.nlm.nih.gov/pubmed/18959476
http://dx.doi.org/10.1371/journal.pbio.0060223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573919/
https://www.ncbi.nlm.nih.gov/pubmed/18959476
http://dx.doi.org/10.1371/journal.pbio.0060223

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