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The Desensitization Gating of the MthK K(+) Channel Is Governed by Its Cytoplasmic Amino Terminus
The RCK-containing MthK channel undergoes two inactivation processes: activation-coupled desensitization and acid-induced inactivation. The acid inactivation is mediated by the C-terminal RCK domain assembly. Here, we report that the desensitization gating is governed by a desensitization domain (DD...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573919/ https://www.ncbi.nlm.nih.gov/pubmed/18959476 http://dx.doi.org/10.1371/journal.pbio.0060223 |