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Male-Specific Association between a γ-Secretase Polymorphism and Premature Coronary Atherosclerosis

BACKGROUND: Atherosclerosis is a common multifactorial disease resulting from an interaction between susceptibility genes and environmental factors. The causative genes that contribute to atherosclerosis are elusive. Based on recent findings with a Wistar rat model, we speculated that the γ-secretas...

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Detalles Bibliográficos
Autores principales: van Loo, Karen M. J., Dejaegere, Tim, van Zweeden, Martine, van Schijndel, Jessica E., Wijmenga, Cisca, Trip, Mieke D., Martens, Gerard J. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573958/
https://www.ncbi.nlm.nih.gov/pubmed/18987747
http://dx.doi.org/10.1371/journal.pone.0003662