NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B

The NMR structure of budding yeast chaperone Chz1 complexed with histones H2A.Z-H2B has been determined. Chz1 forms a long irregular chain capped by two short α-helices, and uses both positively and negatively charged residues to stabilize the histone dimer. A molecular model that docks Chz1 onto th...

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Detalles Bibliográficos
Autores principales: Zhou, Zheng, Feng, Hanqiao, Hansen, D Flemming, Kato, Hidenori, Luk, Ed, Freedberg, Daron I, Kay, Lewis E, Wu, Carl, Bai, Yawen
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574748/
https://www.ncbi.nlm.nih.gov/pubmed/18641662
http://dx.doi.org/10.1038/nsmb.1465
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author Zhou, Zheng
Feng, Hanqiao
Hansen, D Flemming
Kato, Hidenori
Luk, Ed
Freedberg, Daron I
Kay, Lewis E
Wu, Carl
Bai, Yawen
author_facet Zhou, Zheng
Feng, Hanqiao
Hansen, D Flemming
Kato, Hidenori
Luk, Ed
Freedberg, Daron I
Kay, Lewis E
Wu, Carl
Bai, Yawen
author_sort Zhou, Zheng
collection PubMed
description The NMR structure of budding yeast chaperone Chz1 complexed with histones H2A.Z-H2B has been determined. Chz1 forms a long irregular chain capped by two short α-helices, and uses both positively and negatively charged residues to stabilize the histone dimer. A molecular model that docks Chz1 onto the nucleosome has implications for its potential functions.
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spelling pubmed-25747482009-02-01 NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B Zhou, Zheng Feng, Hanqiao Hansen, D Flemming Kato, Hidenori Luk, Ed Freedberg, Daron I Kay, Lewis E Wu, Carl Bai, Yawen Nat Struct Mol Biol Article The NMR structure of budding yeast chaperone Chz1 complexed with histones H2A.Z-H2B has been determined. Chz1 forms a long irregular chain capped by two short α-helices, and uses both positively and negatively charged residues to stabilize the histone dimer. A molecular model that docks Chz1 onto the nucleosome has implications for its potential functions. 2008-07-20 2008-08 /pmc/articles/PMC2574748/ /pubmed/18641662 http://dx.doi.org/10.1038/nsmb.1465 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Zhou, Zheng
Feng, Hanqiao
Hansen, D Flemming
Kato, Hidenori
Luk, Ed
Freedberg, Daron I
Kay, Lewis E
Wu, Carl
Bai, Yawen
NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title_full NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title_fullStr NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title_full_unstemmed NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title_short NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B
title_sort nmr structure of chaperone chz1 complexed with histones h2a.z-h2b
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574748/
https://www.ncbi.nlm.nih.gov/pubmed/18641662
http://dx.doi.org/10.1038/nsmb.1465
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