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Innate immunity and intestinal microbiota in the development of Type 1 diabetes
Type 1 diabetes (T1D) is a debilitating autoimmune disease that results from T cell-mediated destruction of insulin-producing β cells. Its incidence has increased during the past several decades in developed countries 1, 2, suggesting that changes in the environment (including human microbial enviro...
Autores principales: | Wen, Li, Ley, Ruth E., Volchkov, Pavel V., Stranges, Peter B., Avanesyan, Lia, Stonebraker, Austin C., Hu, Changyun, Wong, F. Susan, Szot, Gregory L., Bluestone, Jeffrey A., Gordon, Jeffrey I., Chervonsky, Alexander V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574766/ https://www.ncbi.nlm.nih.gov/pubmed/18806780 http://dx.doi.org/10.1038/nature07336 |
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