Reduced-representation methylation mapping

The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during different...

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Detalles Bibliográficos
Autores principales: Jeddeloh, Jeffrey A, Greally, John M, Rando, Oliver J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575507/
https://www.ncbi.nlm.nih.gov/pubmed/18771577
http://dx.doi.org/10.1186/gb-2008-9-8-231
Descripción
Sumario:The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

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