Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays

INTRODUCTION: In critically ill patients, the massive release of angiopoietin-2 (Ang-2) from endothelial Weibel–Palade bodies interferes with constitutive angiopoietin-1 (Ang-1)/Tie2 signaling in endothelial cells, thus leading to vascular barrier breakdown followed by leukocyte transmigration and c...

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Detalles Bibliográficos
Autores principales: Lukasz, Alexander, Hellpap, Julian, Horn, Rüdiger, Kielstein, Jan T, David, Sascha, Haller, Hermann, Kümpers, Philipp
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575578/
https://www.ncbi.nlm.nih.gov/pubmed/18664247
http://dx.doi.org/10.1186/cc6966

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