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Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix
INTRODUCTION: Adult mesenchymal stem cell therapy has a potential application in the biological treatment of disc degeneration. Our objectives were: to direct adipose-derived mesenchymal stem cells (AD-MSC) from the sand rat to produce a proteoglycan and collagen type I extracellular matrix (ECM) ri...
Autores principales: | Tapp, Hazel, Deepe, Ray, Ingram, Jane A, Kuremsky, Marshall, Hanley, Edward N, Gruber, Helen E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575603/ https://www.ncbi.nlm.nih.gov/pubmed/18691412 http://dx.doi.org/10.1186/ar2473 |
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