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Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

INTRODUCTION: There is increasing evidence that autoantibodies and immune complexes (ICs) contribute to synovitis in rheumatoid arthritis (RA), yet the autoantigens incorporated in ICs in RA remain incompletely characterised. METHODS: We used the C1q protein to capture ICs from plasma derived from h...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoyan, Okeke, Nwora Lance, Sharpe, Orr, Batliwalla, Franak M, Lee, Annette T, Ho, Peggy P, Tomooka, Beren H, Gregersen, Peter K, Robinson, William H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575608/
https://www.ncbi.nlm.nih.gov/pubmed/18710572
http://dx.doi.org/10.1186/ar2478