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Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease

Primary cilia project from the surface of most vertebrate cells and are thought to be sensory organelles. Defects in primary cilia lead to cystic kidney disease, although the ciliary mechanisms that promote and maintain normal renal function remain incompletely understood. In this work, we generated...

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Detalles Bibliográficos
Autores principales: Jonassen, Julie A., San Agustin, Jovenal, Follit, John A., Pazour, Gregory J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575779/
https://www.ncbi.nlm.nih.gov/pubmed/18981227
http://dx.doi.org/10.1083/jcb.200808137

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