Segregation and activation of myosin IIB creates a rear in migrating cells

We have found that MLC-dependent activation of myosin IIB in migrating cells is required to form an extended rear, which coincides with increased directional migration. Activated myosin IIB localizes prominently at the cell rear and produces large, stable actin filament bundles and adhesions, which...

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Detalles Bibliográficos
Autores principales: Vicente-Manzanares, Miguel, Koach, Margaret A., Whitmore, Leanna, Lamers, Marcelo L., Horwitz, Alan F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575793/
https://www.ncbi.nlm.nih.gov/pubmed/18955554
http://dx.doi.org/10.1083/jcb.200806030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575793/
https://www.ncbi.nlm.nih.gov/pubmed/18955554
http://dx.doi.org/10.1083/jcb.200806030

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