Cargando…
Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation
Platelets play an important role in hemostasis, with inappropriate platelet activation being a major contributor to debilitating and often fatal thrombosis by causing myocardial infarction and stroke. Although current antithrombotic treatment is generally well tolerated and effective, many patients...
Autores principales: | Jones, Sarah, Tucker, Katherine L., Sage, Tanya, Kaiser, William J., Barrett, Natasha E., Lowry, Philip J., Zimmer, Andreas, Hunt, Stephen P., Emerson, Michael, Gibbins, Jonathan M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575837/ https://www.ncbi.nlm.nih.gov/pubmed/17895403 http://dx.doi.org/10.1182/blood-2007-07-103424 |
Ejemplares similares
-
A dual role for integrin-linked kinase in platelets: regulating integrin function and α-granule secretion
por: Tucker, Katherine L., et al.
Publicado: (2008) -
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets
por: Moraes, Leonardo A., et al.
Publicado: (2007) -
Platelet-targeted thrombolysis for treatment of acute ischemic stroke
por: Palazzolo, Jason S., et al.
Publicado: (2022) -
Noncanonical Sonic Hedgehog signaling amplifies platelet reactivity and thrombogenicity
por: Tiwari, Arundhati, et al.
Publicado: (2022) -
Cleavage of talin by calpain promotes platelet-mediated fibrin clot contraction
por: Fong, Karen P., et al.
Publicado: (2021)