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Effect of the assignment of ancestral CpG state on the estimation of nucleotide substitution rates in mammals
BACKGROUND: Molecular evolutionary studies in mammals often estimate nucleotide substitution rates within and outside CpG dinucleotides separately. Frequently, in alignments of two sequences, the division of sites into CpG and non-CpG classes is based simply on the presence or absence of a CpG dinuc...
Autores principales: | Gaffney, Daniel J, Keightley, Peter D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576242/ https://www.ncbi.nlm.nih.gov/pubmed/18826599 http://dx.doi.org/10.1186/1471-2148-8-265 |
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