Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients

BACKGROUND: Non-biological experimental error routinely occurs in microarray data collected in different batches. It is often impossible to compare groups of samples from independent experiments because batch effects confound true gene expression differences. Existing methods can correct for batch e...

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Detalles Bibliográficos
Autores principales: Walker, Wynn L, Liao, Isaac H, Gilbert, Donald L, Wong, Brenda, Pollard, Katherine S, McCulloch, Charles E, Lit, Lisa, Sharp, Frank R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576259/
https://www.ncbi.nlm.nih.gov/pubmed/18937867
http://dx.doi.org/10.1186/1471-2164-9-494

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