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Motion compensation with a scanned ion beam: a technical feasibility study

BACKGROUND: Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment beam. METHODS: Lateral motion components were compensated directly with the beam...

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Autores principales: Grözinger, Sven Oliver, Bert, Christoph, Haberer, Thomas, Kraft, Gerhard, Rietzel, Eike
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576303/
https://www.ncbi.nlm.nih.gov/pubmed/18854012
http://dx.doi.org/10.1186/1748-717X-3-34
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author Grözinger, Sven Oliver
Bert, Christoph
Haberer, Thomas
Kraft, Gerhard
Rietzel, Eike
author_facet Grözinger, Sven Oliver
Bert, Christoph
Haberer, Thomas
Kraft, Gerhard
Rietzel, Eike
author_sort Grözinger, Sven Oliver
collection PubMed
description BACKGROUND: Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment beam. METHODS: Lateral motion components were compensated directly with the beam scanning system by adapting nominal beam positions according to the target motion. Longitudinal motion compensation to mitigate motion induced range changes was performed with a dedicated wedge system that adjusts effective particle energies at isocenter. RESULTS: Lateral compensation performance was better than 1% for a homogeneous dose distribution when comparing irradiations of a stationary radiographic film and a moving film using motion compensation. The accuracy of longitudinal range compensation was well below 1 mm. CONCLUSION: Motion compensation with scanned particle beams is technically feasible with high precision.
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spelling pubmed-25763032008-10-31 Motion compensation with a scanned ion beam: a technical feasibility study Grözinger, Sven Oliver Bert, Christoph Haberer, Thomas Kraft, Gerhard Rietzel, Eike Radiat Oncol Research BACKGROUND: Intrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target motion by tracking with the treatment beam. METHODS: Lateral motion components were compensated directly with the beam scanning system by adapting nominal beam positions according to the target motion. Longitudinal motion compensation to mitigate motion induced range changes was performed with a dedicated wedge system that adjusts effective particle energies at isocenter. RESULTS: Lateral compensation performance was better than 1% for a homogeneous dose distribution when comparing irradiations of a stationary radiographic film and a moving film using motion compensation. The accuracy of longitudinal range compensation was well below 1 mm. CONCLUSION: Motion compensation with scanned particle beams is technically feasible with high precision. BioMed Central 2008-10-14 /pmc/articles/PMC2576303/ /pubmed/18854012 http://dx.doi.org/10.1186/1748-717X-3-34 Text en Copyright © 2008 Grözinger et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Grözinger, Sven Oliver
Bert, Christoph
Haberer, Thomas
Kraft, Gerhard
Rietzel, Eike
Motion compensation with a scanned ion beam: a technical feasibility study
title Motion compensation with a scanned ion beam: a technical feasibility study
title_full Motion compensation with a scanned ion beam: a technical feasibility study
title_fullStr Motion compensation with a scanned ion beam: a technical feasibility study
title_full_unstemmed Motion compensation with a scanned ion beam: a technical feasibility study
title_short Motion compensation with a scanned ion beam: a technical feasibility study
title_sort motion compensation with a scanned ion beam: a technical feasibility study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576303/
https://www.ncbi.nlm.nih.gov/pubmed/18854012
http://dx.doi.org/10.1186/1748-717X-3-34
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