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High-resolution array CGH clarifies events occurring on 8p in carcinogenesis

BACKGROUND: Rearrangement of the short arm of chromosome 8 (8p) is very common in epithelial cancers such as breast cancer. Usually there is an unbalanced translocation breakpoint in 8p12 (29.7 Mb – 38.5 Mb) with loss of distal 8p, sometimes with proximal amplification of 8p11-12. Rearrangements in...

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Detalles Bibliográficos
Autores principales: Cooke, Susanna L, Pole, Jessica CM, Chin, Suet-Feung, Ellis, Ian O, Caldas, Carlos, Edwards, Paul AW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576333/
https://www.ncbi.nlm.nih.gov/pubmed/18840272
http://dx.doi.org/10.1186/1471-2407-8-288