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Canine fibroblast growth factor receptor 3 sequence is conserved across dogs of divergent skeletal size
BACKGROUND: Fibroblast growth factor receptor 3 (FGFR3) is expressed in the growth plate of endochondral bones and serves as a negative regulator of linear bone elongation. Activating mutations severely limit bone growth, resulting in dwarfism, while inactivating mutations significantly enhance bone...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576350/ https://www.ncbi.nlm.nih.gov/pubmed/18940000 http://dx.doi.org/10.1186/1471-2156-9-67 |