Canine fibroblast growth factor receptor 3 sequence is conserved across dogs of divergent skeletal size

BACKGROUND: Fibroblast growth factor receptor 3 (FGFR3) is expressed in the growth plate of endochondral bones and serves as a negative regulator of linear bone elongation. Activating mutations severely limit bone growth, resulting in dwarfism, while inactivating mutations significantly enhance bone...

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Detalles Bibliográficos
Autores principales: Smith, Logan B, Bannasch, Danika L, Young, Amy E, Grossman, Deborah I, Belanger, Janelle M, Oberbauer, Anita M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576350/
https://www.ncbi.nlm.nih.gov/pubmed/18940000
http://dx.doi.org/10.1186/1471-2156-9-67

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