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Diffusional Channeling in the Sulfate-Activating Complex: Combined Continuum Modeling and Coarse-Grained Brownian Dynamics Studies

Enzymes required for sulfur metabolism have been suggested to gain efficiency by restricted diffusion (i.e., channeling) of an intermediate APS(2–) between active sites. This article describes modeling of the whole channeling process by numerical solution of the Smoluchowski diffusion equation, as w...

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Detalles Bibliográficos
Autores principales:	Cheng, Yuhui, Chang, Chia-en A., Yu, Zeyun, Zhang, Yongjie, Sun, Meihao, Leyh, Thomas S., Holst, Michael J., McCammon, J. Andrew
Formato:	Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2008
Materias:	Channels, Receptors, and Electrical Signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576392/ https://www.ncbi.nlm.nih.gov/pubmed/18689458 http://dx.doi.org/10.1529/biophysj.108.140038

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