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The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer

BACKGROUND: Development of metastasis in breast cancer is a multi-step process comprising changes in cytoskeletal structure and gene expression of tumour cells leading to changes in cell adhesion and motility. The Rho GTPase proteins, which function as guanine nucleotide regulated binary switches, g...

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Detalles Bibliográficos
Autores principales:	Lane, Jane, Martin, Tracey A, Mansel, Robert E, Jiang, Wen G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576462/ https://www.ncbi.nlm.nih.gov/pubmed/18925966 http://dx.doi.org/10.1186/1477-7800-5-23

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