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Downregulation of LIM kinase 1 suppresses ocular inflammation and fibrosis

PURPOSE: The purpose of this study was to determine if downregulation of LIM kinase 1 (LIMK1) by genetic deletion or direct application of LIMK1-targeted siRNA could suppress TGF-β mediated ocular inflammation and fibrosis. METHODS: LIMK1 specific siRNAs designed from the human sequence were transfe...

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Detalles Bibliográficos
Autores principales:	Gorovoy, Matvey, Koga, Takahisa, Shen, Xiang, Jia, Zhengping, Yue, Beatrice Y., Voyno-Yasenetskaya, Tatyana
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Vision 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576479/ https://www.ncbi.nlm.nih.gov/pubmed/18978953

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