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Adult-Like Anti-Mycobacterial T Cell and In Vivo Dendritic Cell Responses Following Neonatal Immunization with Ag85B-ESAT-6 in the IC31® Adjuvant

BACKGROUND: With the exception of some live vaccines, e.g. BCG, subunit vaccines formulated with “classical” adjuvants do not induce similar responses in neonates as in adults. The usual neonatal profile is characterized by lower levels of TH1-associated biomarkers. This has hampered the development...

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Detalles Bibliográficos
Autores principales:	Kamath, Arun T., Rochat, Anne-Françoise, Valenti, Mario P., Agger, Else Marie, Lingnau, Karen, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577009/ https://www.ncbi.nlm.nih.gov/pubmed/18997860 http://dx.doi.org/10.1371/journal.pone.0003683

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