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Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

BACKGROUND: X chromosome inactivation is the mechanism used in mammals to achieve dosage compensation of X-linked genes in XX females relative to XY males. Chromosome silencing is triggered in cis by expression of the non-coding RNA Xist. As such, correct regulation of the Xist gene promoter is requ...

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Detalles Bibliográficos
Autores principales:	Nesterova, Tatyana B, Popova, Bilyana C, Cobb, Bradley S, Norton, Sara, Senner, Claire E, Tang, Y Amy, Spruce, Thomas, Rodriguez, Tristan A, Sado, Takashi, Merkenschlager, Matthias, Brockdorff, Neil
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577046/ https://www.ncbi.nlm.nih.gov/pubmed/19014663 http://dx.doi.org/10.1186/1756-8935-1-2

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