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Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities

Human vaccinia-related kinase (VRK) 1 is a novel serine-threonine kinase that regulates several transcription factors, nuclear envelope assembly, and chromatin condensation and is also required for cell cycle progression. The regulation of this kinase family is unknown. Mass spectrometry has permitt...

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Detalles Bibliográficos
Autores principales:	Sanz-García, Marta, López-Sánchez, Inmaculada, Lazo, Pedro A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577208/ https://www.ncbi.nlm.nih.gov/pubmed/18617507 http://dx.doi.org/10.1074/mcp.M700586-MCP200

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